The following screens will guide you through the electronic submission process for submitting a Solicited Manuscript to Science Translational Medicine. Please note our general instructions for authors.

After you log in, you will first be asked to fill out a conflict of interest form (click here for our policy and a copy of the forms) and complete an exclusive Publishing License via a click-through (click here for more information on this license). Please have relevant conflict of interest information ready for yourself and all co-authors, and for the license, your title and author list. Note that once you have filled out and transmitted these forms, you will not be able to make any revisions to them via this web site. Any proposed modifications must be sent directly to the Science Translational Medicine editorial office. You can, however, complete these forms and return later to upload your files. You can also decide to send us a hard copy rather than filling out the forms online.

Please submit your text as a MS Word file and figures as PDF, EPS, or JPG files. If you are working in LaTeX, please see our instructions and use our LaTeX template, and include both a PS file and the source files in your upload.

Our submission site will ask you to verify or add information for the following fields. Some information will already be entered. Please correct this information as appropriate:

• Names and addresses, including email addresses, of all authors
• Text version of the title and abstract (you can paste this in from your manuscript file); Please correct the title.
• A text version of the cover letter. Please provide future contact and any travel information for the corresponding author (and alternate contacts if appropriate). Please do not upload a "cover letter" file.

Our submission site allows you to return repeatedly to the site and update information BEFORE completing your final submission. You can use your User ID and password to return at any time to complete your submission. You can also use your Web Submission ID, which you will see once you click continue below. However, once you indicate that a submission is complete, you will not be allowed to update files via this web site, unless we detect an error (you will be notified; see below). If you later find that you have uploaded an incorrect file or have not uploaded your complete manuscript, please contact the Science Translational Medicine editorial office (scitranslmededitors@aaas.org).

After you have submitted a manuscript, we will check the files you have uploaded to be sure that they are readable and in a correct format. We will notify you, usually within one business day, of any errors by email and may ask you to upload one or more files again.

This form is for submission of Science Translational Medicine manuscripts only. Supplemental material, such as related papers that are not yet published, should be sent by mail to the appropriate address below. Please include your submission ID as reference.